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Preparative Ion Exchange Resins

Preparative ion exchange resins are specialized resins used for large-scale purification, separation, and concentration of biomolecules, pharmaceuticals, and other valuable compounds in preparative chromatography. They play a crucial role in industries such as biotechnology, pharmaceuticals, food processing, and water treatment.

The CK grade resins

The CK grade resins are based on a crosslinked polystyrene matrix having sulfonic acid groups with a sodium counter-ion for easy substitution. With varying the crosslinking degree or the DVB content (divinyl-benzene ratio) and the bead size of these resins, one can control the efficiency and the resolution in the separation of amino-acids, carbohydrates, sugars, organic acids and amines etc… These styrenic matrices have excellent mechanical strength with wide range pH stability (1 to 14) and resistance to high temperatures (up to 120 °C operating temperature).

The CA grade resins

The CA grade resins are based on a crosslinked polystyrene matrix having quaternary amine groups (trimethyl amine) with a chloride counter-ion for easy substitution. With varying the crosslinking degree or the DVB content (divinyl-benzene ratio) and the bead size of these resins, one can control the efficiency and the resolution in the separation of nucleotides, carbohydrates, sugars, carboxylic acids and anionic substances (e.g. Humic) etc… These styrenic matrices have excellent mechanical strength with wide range pH stability (1 to 14) and resistance to high temperatures (up to 60 °C operating temperature).

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